Madame Web, also known as Cassandra Webb, is a fictional character featured in American comic books published by Marvel Comics. She made her debut in The Amazing Spider-Man #210, which was released in November 1980, and was co-created by writer Denny O’Neil and artist John Romita Jr..
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Within the Spider-Man comic book series, she typically assumes the role of a supporting character, appearing as an elderly woman afflicted with myasthenia gravis, who relies on a life support system resembling a spiderweb.
Madame Web possessed clairvoyant and precognitive abilities, and she initially appeared to aid Spider-Man in his efforts to locate a kidnapped individual. Notably, she was one of the mutants unaffected by the events of the Decimation storyline.
In the storyline known as Grim Hunt, she came under attack from Sarah and Ana Kravinoff, ultimately succumbing to their assault. However, just before her demise, she managed to transfer her precognitive powers and her condition of blindness to Julia Carpenter, who then took up the mantle of the next Madame Web. Subsequently,
Madame Web was resurrected by Ben Reilly but later fell victim to the Carrion Virus. It’s worth mentioning that Madame Web is also the grandmother of the fourth Spider-Woman, Charlotte Witter.